What are allergies?: Feature Article

What are allergies? This is a very good question, especially if you suffer the watery eyes, itchy eyes, watery nose, asthma, wheezing, coughing, or other symptoms of allergies.
A very simplified explanation of what allergies are is they are simply the immune system's incorrect response to a foreign substance. For some people, exposure to what is normally a harmless substance, such as pollen, will cause the immune system to react as if the substance is harmful. The response is the symptoms mentioned above, which can be very unpleasant for the sufferer.
The substances that cause allergies are called allergens. There are a lot of allergens, and not everyone is allergic to all of them, but some people suffer from many allergies, and all to different degrees. Some people, for example, are only slightly allergic to peanuts, while others could die if they ingest one.
When you come into contact with an allergen, you may experience a number of allergic symptoms. The most typical include itchy, watery nose and eyes; asthma symptoms such as wheezing and coughing; or hives. The symptoms can become more severe.
Basically, if you have an allergy, you will experience and allergic reaction. So, that leads to the question, what is an allergic reaction?
The answer is that it is a hypersensitive response of your body, and a result of how the following three factors interact with the body:
- The allergen. Allergens vary from person to person, but include pollen, mold, dust mites, certain foods, latex, animal dander, and others.
- Mast cells. Mast cells are found throughout the body, however most reside in connective tissues such as those of the skin, tongue, the lining of the nose and intestinal tract, the lungs, and upper airways. (which as you can see are the areas where most symptoms of allergies manifest themselves)
- Immunoglobulin E (IgE) - IgE is an allergic antibody, a type of protein made by the immune system to recognize and fight specific body "invaders." IgE coats the surface of the mast cells in tissues, manifesting itself as your "allergic reaction" with watery eyes and nose, itchiness, hives, etc.
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So, the way allergies work is that if your body is exposed to an allergen and decides that it is harmful to the body, such as pollen, or dander, your body will produce a large amount of the corresponding IgE antibodies, for example, pollen IgE antibodies. The IgE antibodies cause the mast cells to release inflammatory chemicals that cause swelling of tissues, as well as histamine and several other chemicals that cause itching, engorgement of blood vessels, increased secretions, and bronchospasm (tightening of muscles that surround the airways). Some of these chemicals attract white blood cells known as eosinophils. The eosinophils add more inflammatory chemicals. Thus, you react as a defense mechanism.
Helpful Resources: Overview of Allergies This site provides a great overview of what allergies are, what the symptoms are, how you get them, and whether or not you can prevent them. It is very detailed and fairly accurate. Learn More About Allergies Allergy AAFA Allergies What Allergy is All About Allergies Claritin
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Now there are different types of allergies, there are airborne, and other. If the allergen is in the air, the allergic reaction will occur in the eyes, nose and lungs. If the allergen is ingested, the allergic reaction will occur in the mouth, stomach, and intestines. If you touch the thing you are allergic to the reaction may manifest on the skin. Sometimes enough inflammatory chemicals are released to cause a reaction throughout the body, such as hives, decreased blood pressure, shock, or loss of consciousness. This severe type of reaction is called anaphylaxis and may be life-threatening.
So, as you can see, allergies are abnormal immune system reactions to things that are typically harmless to most people. When you're allergic to something, your immune system mistakenly believes that this substance is harmful to your body. Thus, to protect your body from the substance, the immune system produces antibodies to that allergen. Those antibodies then cause certain cells in the body to release chemicals into the bloodstream, one of which is histamine. This chemical, histamine, acts on a person's eyes, nose, throat, lungs, skin, or gastrointestinal tract and causes the symptoms of the allergic reaction. While very uncomfortable for the person suffering from the histamine, it is actually a protective response from the body. Future exposure to that same allergen, such as pollen each year, will trigger this antibody response again. This means that every time you come into contact with that allergen, you'll have an allergic reaction.
The level of the reaction depends on your body. For some allergic reactions can be mild, like a runny nose; for others they can be severe, like difficulty breathing. An asthma attack, for example, is often an allergic reaction to something that is breathed into the lungs in a person who is susceptible. If the allergic reaction is very very severe, this is called anaphylaxis. Some of the signs of anaphylaxis are difficulty breathing, difficulty swallowing, swelling of the lips, tongue, and throat or other parts of the body, and dizziness or loss of consciousness.
If you are allergic to something to that degree, your symptoms, or in other words, anaphylaxis, will usually occurs minutes after exposure. There are some cases where a delay is possible, however, in general anaphylactic reactions are rare, and can be treated if you seek immediate medical attention.
Some allergies are simply nasal allergy symptoms and hay fever. This type of allergies are referred to as "allergic rhinitis." Many people suffer from seasonal allergic rhinitis. This describes nasal allergies that change with the seasons due to pollen from plants, trees, weeds, grass, etc. These seasonal symptoms arise and are most severe during the pollinating seasons for particular plants. Because some people are allergic to more than one thing, their symptoms may get worse at different times throughout the year, or they may appear constant (perennial) because there is always some plant that is affecting them.
Not everyone gets allergies, whether or not you get them is a combination of what your genetics are like, as most are inherited, and how strong your immune system is. Most allergies are passed on to children by their parents. People inherit a tendency to be allergic, although not to any specific allergen. However, if you are exposed to an allergen when your defenses are low or your immune system is weak, such as when you are pregnant, or right after a viral infection, this can lead to you developing allergies.
Allergic disorders affect more than 20 percent of adults and children (40 to 50 million people) and are the sixth leading cause of chronic illness in the United States, so there is a good chance that you suffer from allergies if you experience symptoms of allergies regularly. Of course, many people realize that allergy symptoms are similar to a cold, and so how do you know if you have allergies or are simply under the weather? If you think you have allergies, don't wait to see if your symptoms will go away. When your symptoms last longer than a week or two and tend to recur, make an appointment with your doctor so a complete medical evaluation can be performed. Usually your doctor will perform a skin test, also called a prick test. This is usually used to identify the substances that are causing your allergy symptoms. It is exactly like what it sounds. The test is performed by pricking your skin with an extract of an allergen, and then evaluating the skin's reaction.
If a skin test cannot be performed, a radioallergosorbent blood test (RAST) may be taken, although its results are not as accurate as a skin test. Basically this tests to see if you have elevated levels of antibodies for specific allergens.
If you are diagnosed with allergies you may be prescribed medications such as antihistamines, decongestants, or a combination of both. Some of these are available over-the-counter so it is possible to self-diagnose and treat, but it is best to consult a physician. You can also get nasal sprays such as topical nasal steroids and cromolyn sodium which can be used to treat allergy symptoms. Immunotherapy, or allergy shots, is recommended for relief that is needed over a long period of time, such as if you are allergic to your pet but want to keep it.
Allergies cannot be prevented, but they can be treated and controlled. You can you're your immune system high in order to prevent developing additional allergies. However, making changes in your environment can greatly limit your exposure to certain allergens and reduce your symptoms.
Allergies are not fun, and can be caused by foods, dust, dander, pollen, and any number of other things. If you think you may have allergies talk to your doctor. The symptoms can be treated and you can live a happy symptom free life, but only if you take the time to check and see if your stuffy nose or watery eyes are allergies not just a common cold.
